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Chanca Piedra - Stone Breaker 30ml

Απόλυτα φυσικό συμπλήρωμα διατροφής που περιέχει εκχύλισμα Φύλλανθου ο οποίος συμβάλλει στη διάλυση των λίθων από τα νεφρά και τη χοληδόχο κύστη. Επίσης υποστηρίζει την καλή λειτουργία του γαστρεντερικού συστήματος. 100% Natural & Organic!!

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Λεπτομέρειες:
Σύμφωνα με τον Ευρωπαϊκό κανονισμό για τους ισχυρισμούς υγείας των συμπληρωμάτων διατροφής η εταιρίας μας δεν μπορεί να δώσει περισσότερες πληροφορίες για το προϊόν μέσα απο το ηλεκτρονικό κατάστημα. Για περισσότερες πληροφορίες επισκεφτείτε ενημερωτικούς ιστότοπους όπως: CHANCA PIEDRA Αριθμός Γνωστοποίησης Ε.Ο.Φ. : 90723/06-09-2018.

Λεπτομέρειες:

Σύμφωνα με τον Ευρωπαϊκό κανονισμό για τους ισχυρισμούς υγείας των συμπληρωμάτων διατροφής η εταιρίας μας δεν μπορεί να δώσει περισσότερες πληροφορίες για το προϊόν μέσα απο το ηλεκτρονικό κατάστημα. Για περισσότερες πληροφορίες επισκεφτείτε ενημερωτικούς ιστότοπους όπως:

CHANCA PIEDRA

Αριθμός Γνωστοποίησης Ε.Ο.Φ. : 90723/06-09-2018.

Συστατικά:
Phyllanthus niruri leaf and stem extract.

Οδηγίες λήψης:
Προσθέστε 1 έως 30 σταγόνες σε 120ml νερό και περιμένετε ένα λεπτό πριν το καταναλώσετε. Ξεκινήστε με 1 σταγόνα δύο φορές την ημέρα (30 λεπτά πριν από τα γεύματα) και αυξήστε σταδιακά μέχρι τις 30 σταγόνες δύο φορές την ημέρα ή σύμφωνα με τις οδηγίες του θεραπευτή σας. Να μην λαμβάνεται κατά την εγκυμοσύνη ή το θηλασμό. Ανακινήστε καλά πριν από κάθε χρήση. Αντενδείξεις: ασθενείς με υπογλυκαιμικά επεισόδια, χαμηλή αρτηριακή πίεση και γυναίκες που επιθυμούν εγκυμοσύνη.

Οδηγίες λήψης:

Προσθέστε 1 έως 30 σταγόνες σε 120ml νερό και περιμένετε ένα λεπτό πριν το καταναλώσετε. Ξεκινήστε με 1 σταγόνα δύο φορές την ημέρα (30 λεπτά πριν από τα γεύματα) και αυξήστε σταδιακά μέχρι τις 30 σταγόνες δύο φορές την ημέρα ή σύμφωνα με τις οδηγίες του θεραπευτή σας.

Να μην λαμβάνεται κατά την εγκυμοσύνη ή το θηλασμό. Ανακινήστε καλά πριν από κάθε χρήση.

Αντενδείξεις: ασθενείς με υπογλυκαιμικά επεισόδια, χαμηλή αρτηριακή πίεση και γυναίκες που επιθυμούν εγκυμοσύνη.

Βίντεο:

Επικοινωνία:
Για Περισσότερες Πληροφορίες μπορείτε να μας καλέσετε από όλη την Ελλάδα: Σταθερό: 210 96 00 416 (Δευτέρα έως Παρασκευή 09:00 με 17:00) Kινητό: 697 6670289 (Δευτέρα έως Κυριακή 10:00 με 20:00)

Επικοινωνία:

Για Περισσότερες Πληροφορίες μπορείτε να μας καλέσετε από όλη την Ελλάδα:

Σταθερό: 210 96 00 416 (Δευτέρα έως Παρασκευή 09:00 με 17:00)

Kινητό: 697 6670289 (Δευτέρα έως Κυριακή 10:00 με 20:00)

Κλινικές μελέτες:
Medical Conditions [peer-reviewed journals] DENGUE VIRUS Suresh, U., Murugan, K., Benelli, G., Nicoletti, M., Barnard, D. R., Panneerselvam, C., ... & Chandramohan, B. (2015). Tackling the growing threat of dengue: Phyllanthus niruri-mediated synthesis of silver nanoparticles and their mosquitocidal properties against the dengue vector Aedes aegypti (Diptera: Culicidae). Parasitology Research, 114(4), 1551-1562. Full Article DIABETES Mediani, A., Abas, F., Maulidiani, M., Khatib, A., Tan, C. P., Ismail, I. S., ... & Lajis, N. H. (2016). Metabolic and biochemical changes in streptozotocin induced obese-diabetic rats treated with Phyllanthus niruri extract.Journal of Pharmaceutical and Biomedical Analysis, 128, 302-312. Full Article Okoli, C. O., Obidike, I. C., Ezike, A. C., Akah, P. A., & Salawu, O. A. (2011). Studies on the possible mechanisms of antidiabetic activity of extract of aerial parts of Phyllanthus niruri. Pharmaceutical Biology, 49(3), 248-255.Full Article Okoli, C. O., Ibiam, A. F., Ezike, A. C., Akah, P. A., & Okoye, T. C. (2010). Evaluation of antidiabetic potentials of Phyllanthus niruri in alloxan diabetic rats. African Journal of Biotechnology, 9(2). Full Article Bavarva, J. H., & Narasimhacharya, A. V. R. L. (2007). Comparative Antidiabetic, Hypolipidemic, and Antioxidant Properties of Phyllanthus niruri. in Normal and Diabetic Rats. Pharmaceutical Biology, 45(7), 569-574. Full Article HEPATITIS B Liu, S., Wei, W., Li, Y., Lin, X., Shi, K., Cao, X., & Zhou, M. (2014). In vitro and in vivo anti-hepatitis B virus activities of the lignan nirtetralin B isolated from Phyllanthus niruri L. Journal of Ethnopharmacology, 157, 62-68. Full Article Wei, W., Li, X., Wang, K., Zheng, Z., & Zhou, M. (2012). Lignans with Anti‐Hepatitis B Virus Activities from Phyllanthus niruri L. Phytotherapy Research, 26(7), 964-968. Full Article HIV Naik, A. D., & Juvekar, A. R. (2003). Effects of alkaloidal extract of Phyllanthus niruri on HIV replication. Indian Journal of Medical Sciences, 57(9), 387-393. Full Article LIVER CIRRHOSIS Amin, Z. A., Bilgen, M., Alshawsh, M. A., Ali, H. M., Hadi, A. H. A., & Abdulla, M. A. (2012). Protective role of Phyllanthus niruri extract against thioacetamide-induced liver cirrhosis in rat model. Evidence-Based Complementary and Alternative Medicine, 2012. Full Article UROLITHIASIS (KIDNEY STONES) Boim, M. A., Heilberg, I. P., & Schor, N. (2010). Phyllanthus niruri as a promising alternative treatment for nephrolithiasis. International Braz J Urol, 36(6), 657-664. Full Article MALARIA Tona, L., Mesia, K., Ngimbi, N. P., Chrimwami, B., Okond'Ahoka, Cimanga, K., ... & Pieters, L. (2001). In-vivo antimalarial activity of Cassia occidentalism Morinda morindoides and Phyllanthus niruri. Annals of Tropical Medicine & Parasitology, 95(1), 47-57. Full Article TUMORS Sharma, P., Parmar, J., Verma, P., Sharma, P., & Goyal, P. K. (2009). Anti-tumor activity of Phyllanthus niruri (a medicinal plant) on chemical-induced skin carcinogenesis in mice. Asian Pac J Cancer Prev, 10(6), 1089-1094.Full Article Medicinal Properties [peer-reviewed journals] ANTIBACTERIAL Ekwenye, U. N., & Njoku, N. U. (2006). Antibacterial effect of Phyllanthus niruri (Chanca Piedra) on three enteropathogens in Man. International Journal of Molecular Medicine and Advance Sciences, 2(2), 184-189. Full Article ANTIHYPERURICEMIC Murugaiyah, V., & Chan, K. L. (2009). Mechanisms of antihyperuricemic effect of Phyllanthus niruri and its lignan constituents. Journal of Ethnopharmacology, 124(2), 233-239. Full Article ANTIOXIDANT Sabir, S. M., & Rocha, J. B. T. (2008). Water-extractable phytochemicals from Phyllanthus niruri exhibit distinct in vitro antioxidant and in vivo hepatoprotective activity against paracetamol-induced liver damage in mice.Food Chemistry, 111(4), 845-851. Full Article Bhattacharjee, R., & Sil, P. C. (2007). Protein isolate from the herb, Phyllanthus niruri L.(Euphorbiaceae), plays hepatoprotective role against carbon tetrachloride induced liver damage via its antioxidant properties. Food and Chemical Toxicology, 45(5), 817-826. Full Article Chatterjee, M., Sarkar, K., & Sil, P. C. (2006). Herbal (Phyllanthus niruri) protein isolate protects liver from nimesulide induced oxidative stress. Pathophysiology, 13(2), 95-102. Full Article Chatterjee, M., & Sil, P. C. (2006). Hepatoprotective effect of aqueous extract of Phyllanthus niruri on nimesulide-induced oxidative stress in vivo. Indian Journal of Biochemistry & Biophysics, 43, 299-305. Full Article Bhattacharjee, R., & Sil, P. C. (2006). The protein fraction of Phyllanthus niruri plays a protective role against acetaminophen induced hepatic disorder via its antioxidant properties. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 20(7), 595-601.Full Article Harish, R., & Shivanandappa, T. (2006). Antioxidant activity and hepatoprotective potential of Phyllanthus niruri. Food Chemistry, 95(2), 180-185. Full Article ANTIMICROBIAL Ranilla, L. G., Apostolidis, E., & Shetty, K. (2012). Antimicrobial activity of an Amazon medicinal plant (Chancapiedra)(Phyllanthus niruri L.) against Helicobacter pylori and lactic acid bacteria. Phytotherapy Research, 26(6), 791-799. Full Article ANTI-INFLAMMATORY Ifeoma, O., Samuel, O., Itohan, A. M., & Adeola, S. O. (2013). Isolation, fractionation and evaluation of the antiplasmodial properties of Phyllanthus niruri resident in its chloroform fraction. Asian Pacific Journal of Tropical Medicine, 6(3), 169-175. Full Article ANTIPLASMODIAL Ifeoma, O., Samuel, O., Itohan, A. M., & Adeola, S. O. (2013). Isolation, fractionation and evaluation of the antiplasmodial properties of Phyllanthus niruri resident in its chloroform fraction. Asian Pacific Journal of Tropical Medicine, 6(3), 169-175. Full Article Soh, P. N., Banzouzi, J. T., Mangombo, H., Lusakibanza, M., Bulubulu, F. O., Tona, L., ... & Luyindula, S. N. (2009).Antiplasmodial activity of various parts of Phyllanthus niruri according to its geographical distribution. African journal of Pharmacy and Pharmacology, 3(12), 598-601. Full Article Mustofa, S. E., & Wahyuono, S. (2007). In vitro and in vivo antiplasmodial activity and cytotoxicity of extracts of Phyllanthus niruri L. herbs traditionally used to treat malaria in Indonesia. Southeast Asian J Trop Med Public Health, 38(4), 609-615. Full Article Cimanga, R. K., Tona, L., Luyindula, N., Mesia, K., Lusakibanza, M., Musuamba, C. T., ... & Totté, J. (2004). In vitro antiplasmodial activity of callus culture extracts and fractions from fresh apical stems of Phyllanthus niruri L.(Euphorbiaceae): part 2. Journal of Ethnopharmacology, 95(2-3), 399-404. Full Article HEPATOPROTECTIVE Ooi, K. L., Loh, S. I., Sattar, M. A., Muhammad, T. S. T., & Sulaiman, S. F. (2015). Cytotoxic, caspase-3 induction and in vivo hepatoprotective effects of phyllanthin, a major constituent of Phyllanthus niruri. Journal of Functional Foods, 14, 236-243. Full Article IBS Giribabu, N., Rao, P. V., Kumar, K. P., Muniandy, S., Swapna Rekha, S., & Salleh, N. (2014). Aqueous extract of Phyllanthus niruri leaves displays in vitro antioxidant activity and prevents the elevation of oxidative stress in the kidney of streptozotocin-induced diabetic male rats. Evidence-Based Complementary and Alternative Medicine, 2014. Full Article IMMUNOMODULATING Nworu, C. S., Akah, P. A., Okoye, F. B. C., Proksch, P., & Esimone, C. O. (2010). The effects of Phyllanthus niruri aqueous extract on the activation of murine lymphocytes and bone marrow-derived macrophages.Immunological investigations, 39(3), 245-267. Full Article VARIOUS PROPERTIES Amin, Z. A., Abdulla, M. A., Ali, H. M., Alshawsh, M. A., & Qadir, S. W. (2012). Assessment of in vitro antioxidant, antibacterial and immune activation potentials of aqueous and ethanol extracts of Phyllanthus niruri. Journal of the Science of Food and Agriculture, 92(9), 1874-1877. Full Article Bagalkotkar, G., Sagineedu, S. R., Saad, M. S., & Stanslas, J. (2006). Phytochemicals from Phyllanthus niruri Linn. and their pharmacological properties: a review. Journal of Pharmacy and Pharmacology, 58(12), 1559-1570. Full Article

Κλινικές μελέτες:

Medical Conditions [peer-reviewed journals]

DENGUE VIRUS

Suresh, U., Murugan, K., Benelli, G., Nicoletti, M., Barnard, D. R., Panneerselvam, C., ... & Chandramohan, B. (2015). Tackling the growing threat of dengue: Phyllanthus niruri-mediated synthesis of silver nanoparticles and their mosquitocidal properties against the dengue vector Aedes aegypti (Diptera: Culicidae). Parasitology Research, 114(4), 1551-1562. Full Article

DIABETES

Mediani, A., Abas, F., Maulidiani, M., Khatib, A., Tan, C. P., Ismail, I. S., ... & Lajis, N. H. (2016). Metabolic and biochemical changes in streptozotocin induced obese-diabetic rats treated with Phyllanthus niruri extract.Journal of Pharmaceutical and Biomedical Analysis, 128, 302-312. Full Article

Okoli, C. O., Obidike, I. C., Ezike, A. C., Akah, P. A., & Salawu, O. A. (2011). Studies on the possible mechanisms of antidiabetic activity of extract of aerial parts of Phyllanthus niruri. Pharmaceutical Biology, 49(3), 248-255.Full Article

Okoli, C. O., Ibiam, A. F., Ezike, A. C., Akah, P. A., & Okoye, T. C. (2010). Evaluation of antidiabetic potentials of Phyllanthus niruri in alloxan diabetic rats. African Journal of Biotechnology, 9(2). Full Article

Bavarva, J. H., & Narasimhacharya, A. V. R. L. (2007). Comparative Antidiabetic, Hypolipidemic, and Antioxidant Properties of Phyllanthus niruri. in Normal and Diabetic Rats. Pharmaceutical Biology, 45(7), 569-574. Full Article

HEPATITIS B

Liu, S., Wei, W., Li, Y., Lin, X., Shi, K., Cao, X., & Zhou, M. (2014). In vitro and in vivo anti-hepatitis B virus activities of the lignan nirtetralin B isolated from Phyllanthus niruri L. Journal of Ethnopharmacology, 157, 62-68. Full Article

Wei, W., Li, X., Wang, K., Zheng, Z., & Zhou, M. (2012). Lignans with Anti‐Hepatitis B Virus Activities from Phyllanthus niruri L. Phytotherapy Research, 26(7), 964-968. Full Article

HIV

Naik, A. D., & Juvekar, A. R. (2003). Effects of alkaloidal extract of Phyllanthus niruri on HIV replication. Indian Journal of Medical Sciences, 57(9), 387-393. Full Article

LIVER CIRRHOSIS

Amin, Z. A., Bilgen, M., Alshawsh, M. A., Ali, H. M., Hadi, A. H. A., & Abdulla, M. A. (2012). Protective role of Phyllanthus niruri extract against thioacetamide-induced liver cirrhosis in rat model. Evidence-Based Complementary and Alternative Medicine, 2012. Full Article

UROLITHIASIS (KIDNEY STONES)

Boim, M. A., Heilberg, I. P., & Schor, N. (2010). Phyllanthus niruri as a promising alternative treatment for nephrolithiasis. International Braz J Urol, 36(6), 657-664. Full Article

MALARIA

Tona, L., Mesia, K., Ngimbi, N. P., Chrimwami, B., Okond'Ahoka, Cimanga, K., ... & Pieters, L. (2001). In-vivo antimalarial activity of Cassia occidentalism Morinda morindoides and Phyllanthus niruri. Annals of Tropical Medicine & Parasitology, 95(1), 47-57. Full Article

TUMORS

Sharma, P., Parmar, J., Verma, P., Sharma, P., & Goyal, P. K. (2009). Anti-tumor activity of Phyllanthus niruri (a medicinal plant) on chemical-induced skin carcinogenesis in mice. Asian Pac J Cancer Prev, 10(6), 1089-1094.Full Article

Medicinal Properties [peer-reviewed journals]

ANTIBACTERIAL

Ekwenye, U. N., & Njoku, N. U. (2006). Antibacterial effect of Phyllanthus niruri (Chanca Piedra) on three enteropathogens in Man. International Journal of Molecular Medicine and Advance Sciences, 2(2), 184-189. Full Article

ANTIHYPERURICEMIC

Murugaiyah, V., & Chan, K. L. (2009). Mechanisms of antihyperuricemic effect of Phyllanthus niruri and its lignan constituents. Journal of Ethnopharmacology, 124(2), 233-239. Full Article

ANTIOXIDANT

Sabir, S. M., & Rocha, J. B. T. (2008). Water-extractable phytochemicals from Phyllanthus niruri exhibit distinct in vitro antioxidant and in vivo hepatoprotective activity against paracetamol-induced liver damage in mice.Food Chemistry, 111(4), 845-851. Full Article

Bhattacharjee, R., & Sil, P. C. (2007). Protein isolate from the herb, Phyllanthus niruri L.(Euphorbiaceae), plays hepatoprotective role against carbon tetrachloride induced liver damage via its antioxidant properties. Food and Chemical Toxicology, 45(5), 817-826. Full Article

Chatterjee, M., Sarkar, K., & Sil, P. C. (2006). Herbal (Phyllanthus niruri) protein isolate protects liver from nimesulide induced oxidative stress. Pathophysiology, 13(2), 95-102. Full Article

Chatterjee, M., & Sil, P. C. (2006). Hepatoprotective effect of aqueous extract of Phyllanthus niruri on nimesulide-induced oxidative stress in vivo. Indian Journal of Biochemistry & Biophysics, 43, 299-305. Full Article

Bhattacharjee, R., & Sil, P. C. (2006). The protein fraction of Phyllanthus niruri plays a protective role against acetaminophen induced hepatic disorder via its antioxidant properties. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 20(7), 595-601.Full Article

Harish, R., & Shivanandappa, T. (2006). Antioxidant activity and hepatoprotective potential of Phyllanthus niruri. Food Chemistry, 95(2), 180-185. Full Article

ANTIMICROBIAL

Ranilla, L. G., Apostolidis, E., & Shetty, K. (2012). Antimicrobial activity of an Amazon medicinal plant (Chancapiedra)(Phyllanthus niruri L.) against Helicobacter pylori and lactic acid bacteria. Phytotherapy Research, 26(6), 791-799. Full Article

ANTI-INFLAMMATORY

Ifeoma, O., Samuel, O., Itohan, A. M., & Adeola, S. O. (2013). Isolation, fractionation and evaluation of the antiplasmodial properties of Phyllanthus niruri resident in its chloroform fraction. Asian Pacific Journal of Tropical Medicine, 6(3), 169-175. Full Article

ANTIPLASMODIAL

Soh, P. N., Banzouzi, J. T., Mangombo, H., Lusakibanza, M., Bulubulu, F. O., Tona, L., ... & Luyindula, S. N. (2009).Antiplasmodial activity of various parts of Phyllanthus niruri according to its geographical distribution. African journal of Pharmacy and Pharmacology, 3(12), 598-601. Full Article

Mustofa, S. E., & Wahyuono, S. (2007). In vitro and in vivo antiplasmodial activity and cytotoxicity of extracts of Phyllanthus niruri L. herbs traditionally used to treat malaria in Indonesia. Southeast Asian J Trop Med Public Health, 38(4), 609-615. Full Article

Cimanga, R. K., Tona, L., Luyindula, N., Mesia, K., Lusakibanza, M., Musuamba, C. T., ... & Totté, J. (2004). In vitro antiplasmodial activity of callus culture extracts and fractions from fresh apical stems of Phyllanthus niruri L.(Euphorbiaceae): part 2. Journal of Ethnopharmacology, 95(2-3), 399-404. Full Article

HEPATOPROTECTIVE

Ooi, K. L., Loh, S. I., Sattar, M. A., Muhammad, T. S. T., & Sulaiman, S. F. (2015). Cytotoxic, caspase-3 induction and in vivo hepatoprotective effects of phyllanthin, a major constituent of Phyllanthus niruri. Journal of Functional Foods, 14, 236-243. Full Article

IBS

Giribabu, N., Rao, P. V., Kumar, K. P., Muniandy, S., Swapna Rekha, S., & Salleh, N. (2014). Aqueous extract of Phyllanthus niruri leaves displays in vitro antioxidant activity and prevents the elevation of oxidative stress in the kidney of streptozotocin-induced diabetic male rats. Evidence-Based Complementary and Alternative Medicine, 2014. Full Article

IMMUNOMODULATING

Nworu, C. S., Akah, P. A., Okoye, F. B. C., Proksch, P., & Esimone, C. O. (2010). The effects of Phyllanthus niruri aqueous extract on the activation of murine lymphocytes and bone marrow-derived macrophages.Immunological investigations, 39(3), 245-267. Full Article

VARIOUS PROPERTIES

Amin, Z. A., Abdulla, M. A., Ali, H. M., Alshawsh, M. A., & Qadir, S. W. (2012). Assessment of in vitro antioxidant, antibacterial and immune activation potentials of aqueous and ethanol extracts of Phyllanthus niruri. Journal of the Science of Food and Agriculture, 92(9), 1874-1877. Full Article

Bagalkotkar, G., Sagineedu, S. R., Saad, M. S., & Stanslas, J. (2006). Phytochemicals from Phyllanthus niruri Linn. and their pharmacological properties: a review. Journal of Pharmacy and Pharmacology, 58(12), 1559-1570. Full Article